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Sindola 2.5mg Tablet 10pcs
Mirogabalin binds selectively and potently to the α2δ subunits of voltage-gated calcium channels (VGCCs). This reduces calcium (Ca²⁺) influx and neurotransmission in the dorsal root ganglia (DRG), inhibiting the release of neurotransmitters in presynaptic neuron endings. This mechanism reduces neuronal hyperexcitability and alleviates pain.
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✅ Description:
Mirogabalin Besylate is prescribed for the treatment of:
- Neuropathic Pain
- Diabetic Peripheral Neuropathic Pain (DPNP)
- Postherpetic Neuralgia (PHN)
- Peripheral Neuropathic Pain (PNP)
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ Commonly reported side effects include:
- Somnolence
- Dizziness
- Edema
- Weight Gain
If severe symptoms like loss of consciousness, jaundice, or persistent dizziness occur, discontinue use and consult a doctor.
✔️ Dosage: Sindola 2.5
- Adults: The initial dose is 5 mg taken orally twice daily. The dose may be increased by 5 mg weekly to a maximum of 15 mg twice daily.
- Adjustments should be made based on age and symptoms.
- Always follow the doctor’s advice for dosage.
✔️ Drug Interactions
- Cimetidine and Probenecid may increase Mirogabalin plasma concentrations.
- Combining Mirogabalin with lorazepam or alcohol can potentiate CNS depressive effects (e.g., drowsiness or sedation).
- Mirogabalin does not induce or inhibit cytochrome P450 isoenzymes.
✔️ Contraindications
- Hypersensitivity to Mirogabalin.
- Patients with mild to moderate hepatic or renal impairment.
✔️ Precautions & Warnings
- This medication may cause drowsiness, dizziness, or loss of consciousness. Avoid activities requiring alertness, such as driving or operating machinery.
- Use with caution in elderly patients due to an increased risk of falls and fractures.
- May cause blurred vision or double vision.
- Monitor for signs of weight gain.
- In case of allergic reactions, stop taking the medication and seek immediate medical attention.
✔️ Storage Instructions
- Store below 30°C in a dry place, away from light and moisture.
- Keep out of reach of children.
Disclaimer:
ePharma sole intention is to ensure that its consumers get proper
information as musch as possible. Although we do not guarantee the
accuracy and the completeness of the information that provided and
here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
for the advice of a qualified physician. This may not cover
everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
intend to support, not replace, the doctor-patient relationship.
